Kate Spade, the world-renowned fashion designer who was found dead of an apparent suicide, long suffered from depression and anxiety and had been under treatment for five years, her husband and business partner said Wednesday.

“She was actively seeking help and working closely with her doctors to treat her disease, one that takes far too many lives. We were in touch with her the night before and she sounded happy,” Andy Spade said in a statement.

“There was no indication and no warning that she would do this. It was a complete shock. And it clearly wasn’t her. There were personal demons she was battling,” he said.

Andy Spade acknowledged that he and his wife had been living apart for the last 10 months, maintaining different apartments a few blocks from each other in Manhattan. He said the couple was not legally separated and “never even discussed divorce.”

“We ate many meals together as a family and continued to vacation together as a family. Our daughter was our priority. … We were…