In a world first, cannabis-based drugs are being compared to fentanyl as an alternative to breakthrough pain.

The clinical trial is being facilitated by Santé Cannabis, an independently credentialed research organization based out of Montreal. The study will compare the effects of cannabinoids produced by Tetra Bio-Pharma, a biopharmaceutical leader in cannabinoid-based drug discovery and development, in comparison to fentanyl, an opioid that is linked to hundreds of accidental overdoses in Canada.

According to a statement from Tetra, there were at least 2,923 apparent opioid-related deaths between January and September 2017. Of these overdoses, 92% were accidental and 72% of them involved fentanyl or fentanyl analogues.

Fentanyl is used as a treatment for “breakthrough pain”: a specific kind of “severe pain that erupts while a patient is already medicated with a long-acting…